Chemical name:

Polyoxyethylene glycol, Macrogol 300, Polyethylene glycol 300 Eur. Ph.

Regulatory status:

POLIkol 300PF meets the requirements of the current Ph. Eur. monograph for Macrogol 300


specialty products, specialty additives

Markets and applications:

personal care, pharmaceuticals


antistatics agents, humectants, Lubricants and fluids , softening agents, solubilizers, wetting agents


polyethylene glycols



CAS No.:





POLIkol 300PF belongs to the polyoxyethylene glycol group. This product fulfils the stringent quality requirements of the latest edition of European Pharmacopoeia, which may be classified as a macrogol. Macrogols are the pharmacopoeial name for polyethylene glycols that are used as ingredients in medicines, ointments, dermocosmetics, or other pharmaceutical formulations.

POLIkol 300PF is a colourless, viscous liquid. It is characterised by a wide spectrum of application properties.

Due to their specific properties, macrogols act as solvents and solubilisers for active and auxiliary substances in pharmaceutical formulations. They are substances that improve the rheological properties (an increase in viscosity) of liquid formulations and ointments and also play a stabilising role in the formulations. These products are used as active ingredient binders. They are also used as humectants, i.e., the means of binding the water of the formulation, thereby ensuring even distribution of the components within them.

Moreover, macrogols are safe, non-toxic, and are characterised by a lack of negative environmental classification.

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Properties and applications:

Product advantages:

  • fulfils the stringent quality requirements set out in the latest edition of European Pharmacopoeia,
  • safe and non-toxic substance,
  • possibility of use in pharmaceutical products as a component of medicines, ointments, dermocosmetics and others,
  • possesses softening, dissolving, stabilising, lubricating, solubilising, and moisturizing properties,
  • exhibits anti-static effects,
  • it is used as a humectant or water binder in formulations.


  • ointments and creams,
  • syrups,
  • toothpastes,
  • mouthwashes,
  • tablets,
  • dermocosmetics.

Alternative names:

Show alternative names
PEG; macrogole 300; Polyethylene glycol; (Hide)


polyethylene glycol PEG emollient lubrication anti-static wetting agent cosmetic personal care ph eur pure safe product polyoxyethylene glycol pharmaceutical eur. ph. excipient pharma grade pharmacopoeia excipients API dermocosmetics ointments medicines active substances auxiliary humectants active ingredients binding agents emolients cosmetics
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