Chloroacetic Acid 80% U-P (80% MCAA U-P) is a product of the highest purity available, in which the DCAA content does not exceed 90 ppm. It is intended for use primarily in pharmacy in processes where the DCAA content is critical to the quality of the final product. Chloroacetic acid 80% H-P is highly reactive and is used as a raw material for many important organic compounds. It has a pungent odour, is easily soluble in water, ethanol, methanol, acetone, benzene, chloroform, dimethylsulfoxide, and dimethylformamide. It is poorly soluble in hydrocarbons and their halogenated derivatives.
Chloroacetic acid 80% U-P is produced in a continuous way. The first stage is the chlorination of acetic acid. The second stage of the process is hydrogenation in which most of the dichloroacetic acid (DCAA) is removed. The third step that determines the highest quality of the product is the crystallisation process in which 80% MCAA H-P (500 ppm DCAA) produces an ultra-pure product with a DCAA content of less than 90 ppm.
Monochloroacetic acid is one of the most important intermediates in the chemical industry and is widely used in a large number of organic synthesis processes. This is due to its high reactivity. Both chlorine in the α position and carboxyl group exhibit reactivity in a number of organic reactions, easily forming esters and amides and undergoing many possible substitutions of the chlorine atom.
Due to its properties, mainly C-Cl bond activity, monochloroacetic acid is used in many industries, among which are the production of agrochemicals, plant protection agents, fertilizers, plastics, detergents, paints and coatings, cosmetics and personal hygiene, pulp and paper, pharmaceuticals, food and mining industries. The highest consumption of MCAA is the production of carboxymethylcellulose (CMC).
In the pharmaceutical industry MCAA is used for the production of ibuprofen, diclofenac sodium, caffeine, vitamins (e.g., vitamin B6), glycine, and malonates. Monochloroacetic acid chloride, which is a monochloroacetic acid derivative, is a precursor of adrenaline (epinephrine).
Monochloroacetic acid is an intermediate for the production of plant protection products such as 2,4-dichlorophenoxyacetic acid (2,4-D), thiophosphoric acid esters (e.g., dimethoate), chloroacetyl chloride (CAC), trichloroacetyl chloride (TCAC), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), 2-methyl-4-phenoxyacetic acid (MCPA), and phosphonates (e.g., glyphosate). It is used in the chemical industry as an intermediate in the synthesis of indigo dyes and in the processing of poly (vinyl chloride) as a stabiliser. Monochloroacetic acid is applied in the cosmetics industry for the production of surfactants (betaine), which are made up of hair shampoos and thioglycolic acid (hair styling preparations). In addition, MCAA is used in the production of a wide range of other useful chemicals, such as coumarin, malonic acid, mercaptoacetic acid, aminoacetic acid, cyanoacetic acid, and chloroacetamide.
Markets and applications
Agrochemicals / Crop protection & fertilizers
Mining & Drilling / Oil&gas extraction
Paints & Coatings
Plastics / Polymer additives
Pulp & Paper
Raw materials and intermediates
Raw materials & intermediates