Chemical name:

Polyoxyethylene glycol, Macrogol 400, Polyethylene glycol 400 Eur. Ph.

Regulatory status:

POLIkol 400PF meets the requirements of the current Ph. Eur. monograph for Macrogol 400


specialty products, specialty additives

Markets and applications:

personal care, pharmaceuticals


antistatics agents, humectants, Lubricants and fluids , softening agents, solubilizers, wetting agents


polyethylene glycols



CAS No.:





POLIkol 400PF belongs to the polyoxyethylene glycol group. The product fulfils the stringent quality requirements of the latest edition of European Pharmacopoeia, thanks to which it may be classified as a macrogol. Macrogols are the pharmacopoeial name for polyethylene glycols that are used as ingredients in medicines, ointments, dermocosmetics, or other pharmaceutical formulations.

POLIkol 400PF is characterised by a wide spectrum of application properties. This product exhibits excellent softening, lubricating, solubilising, moisturising, and antistatic properties. It appears as a colourless, viscous liquid.

POLIkol 400PF in pharmaceutical formulations is a component of, among others, eye and ear drops. It can be used as a filling of gelatine capsules. It also occurs as a mixture with Macrogols with a higher molar mass (e.g. greater than 3000 g/mol), taking the form of a paste, which is the basis for ointments. They are also used as humectants, i.e. water-binding agents included in the formulations, which ensure even distribution of their ingredients.

In addition, Macrogols are safe, non-toxic and do not have a negative environmental classification.

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Properties and applications:

Product advantages:

  • fulfils the stringent quality requirements of the latest edition of European Pharmacopoeia,
  • safe and non-toxic substance,
  • possibility of use in pharmaceutical products such as medicines, ointments, dermocosmetics, and others,
  • has softening, dissolving, stabilising, lubricating, solubilising, and moisturising properties,
  • exhibits antistatic effects,
  • it is used as a humectant or water binder in formulations.


  • ointments and creams,
  • syrups,
  • toothpastes,
  • mouthwashes,
  • tablets,
  • dermocosmetics.

Alternative names:

Show alternative names
PEG; macrogole 400; Polyethylene glycol; (Hide)


polyethylene glycol PEG emollient lubrication anti-static wetting agent cosmetic personal care ph eur pure safe produkt polyoxyethylene glycol pharmaceutical eur. ph. excipient pharma grade pharmacopoeia excipients API dermocosmetics ointments medicines active substances auxiliary humectants active ingredients binding agents emolients cosmetics
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