ROKAcet HR40PF produced during ethoxylation of Hydrogenated Castor Oil. Commercial form of these product contains 99% of active substance in the form of clear, yellow viscous liquid to semi – solid. Product is in line with current European Pharmacopeia Monograph for Macrogol Glycerolhydroxystearate which correspond to UPS monograph for Polyoxyl 40 Hydrogenated Castor Oil.
Thanks of post – treatment process product meets strict requirements for low limits of such contaminants as ethylene oxide, 1,4-dioxane or heavy metals which are unacceptable in pharmaceutical formulations, because of undesirable effects on active substance in final dosage forms, and toxicological effect on human health.
ROKAcet HR40PF belongs to the group of non – ionic surfactants. The HLB value for the product counts 14-16 which means that it is very good emulsifier. These property makes ROKAcet HR40PF efficient additive for emulsification of various hydrophobic API’s which improves its bioavailability. Additionally product is characterized by very good solubilizing properties used for production of aqueous solutions of vitamins A, D, E, K, essential oils or any other function ingredient of final dosage forms. It is used widely for oral and topical application because of odorless and tasteless characteristic.
Chemical equivalent of ROKAcet HR40PF is approved by FDA as Inactive Ingredient for Approved Drug Products like: emulsions, creams, oils, capsules, or dental solutions.
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